Thursday, July 11, 2013

Ephedrine

 Ephedrine HCL

Ephedrine 30 mg/1ml 

Each ampoule (1 ml ) contains: Ephedrine HCL 30 mg.

Company Name

CID

Therapeutic Group

ALL OTH A-AS & COPD. SYS

Pharmaceutical form

Ampoule

Package

A carton box containing 100 ampoules each of 1ml.

Indications

- Ephedrine ampoule is used as an emergency method for elevating blood pressure in case reversal of hypotension from spinal or epidural anaesthesia and management of associated bradycardia . - Ephedrine can be used as bronchodilator in case of reversible airways obstruction if clearly needed .

Warning & Precautions

Ephedrine is used with caution in case of hyperthyroidism, diabetes mellitus, ischaemic heart disease, hypertension , Prostatic hypertrophy , hypovolemia, angle closure glaucoma, elderly patients and pregnancy .

Product Type

human

Dosage

-For reversal of hypotension from spinal or epidural anesthesia : 0.25ml of Ephedrine ampoule (30mg/ml) is given by slow intravenous injection and repeated every 3-4 minutes according to response to maximum 1ml (30mg). -Ephedrine ampoule can also be injected intramuscularly or subcutaneously .

Adverse Reactions

- The commonest side effects of Ephedrine are : anxiety , restlessness , insomnia, tremor and tachycardia , Hypertension , seizures , hallucination , palpitation and arrythmias and anginal pain may occur . - Nausea , vomiting , dizziness, anorexia , headache , flushing , urine retention , sweating, hyperglycemia, stinging, contact dermatitis may rearly occur.

Contra Indications

Ephedrine is contra-indicated in case of breast feeding and narrow angle glaucoma .

Drug Interactions

- Risk of hypertension crisis :when Ephedrine given with MAOIs, meclobemide, doxapram or oxytocin . - Hypertensive effect of sympathomimetics is antagonized by antipsychotics. - Ephedrine antagonizes hypotensive effect of adrenergic neuron blockers and may accelerate the metabolism of dexamethasone . - Possible hypertensive effect with furazolidine . - Inhibition of antihypertensive effect of guanethidine . - Increased serum concentration by antacids . - False increased of urine amino acids and urine 5- HIAA
5 EgyDrug Index: Ephedrine Ephedrine 30 mg/1ml  Each ampoule (1 ml ) contains: Ephedrine HCL 30 mg. Company Name CID Therapeutic Group ALL OTH A-AS & CO...

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