Beclosone Non CFC
Beclomethasone dipropionate
Company Name
ADCO
Therapeutic Group
CORTICOIDS INHALANTS
Pharmaceutical form
Inhaler
Package
Canister of 200 inhalations
Indications
A- Oral
Beclomethasone dipropionate is indicated for the control of asthma , particularly in those patients who have been dependent upon either systemically administered corticosteroids or ACTH or who require frequent use of bronchodilating agents .
It is not recommended for the treatment of status asthmaticus .Inhalation of beclomethasone dipropionate is particularly indicated in the following patients :
1- Patients whose asthmatic condition is expected to require long–term maintenance therapy .
2- The majority of severe asthmatics who are dependent on systemic corticosteroids or ACTH .
3- Patients who are receiving intermittent courses of systemic corticosteroids .
4- Patients whose symptoms of bronchial asthma have become less responsive to bronchodilators and require progressively higher doses for relief .
5- Patients for whom bronchodilating compounds are relatively contraindicated such as cardiac patients, etc.
6- Patients whose symptoms are not adequately controlled by combined therapy using bronchodilators with disodium cromoglycate 7- Children with severe asthma; effective control of symptoms has been achieved without the retardation of growth commonly associated with systemic administration of corticosteroids .
Resumption of growth has been reported in children transferred from systemic corticosteroids to beclomethasone dipropionate therapy Pituitary – adrenal suppression resulting from prolonged use of systemic corticosteroids or ACTH , tachycardia and palpitation associated with bronchodilators and gastrointestinal intolerance of aminophylline – like agents can be substantially reduced or eliminated when beclomethasone dipropionate for oral inhalation is prescribed .
B- Intra-Nasal
Beclomethasone dipropionate aerosol , intra-nasaly , is indicated for the treatment of scasonal and perennial allergic rhinitis and vasomotor rhinitis . It may also be used as adjunctive therapy in the medical treatment of nasal polyps .
Warning & Precautions
Beclosone is not to be regarded as a bronchodilator and is not recommended for rapid relief of bronchospasm . Patients should be instructed to contact their physicians immediately when asthmatic episodes are not responsive to bronchodilators during treatment with Beclosone , during such episodes , patients may require systemic corticosteroid therapy . Do not exceed the prescribed dose Beclosone inhaler should be used with caution in patients with active or quiescent tuberculous infections of the respiratory tract .
Product Type
Human
Dosage
For Oral Inhalation :
The usual recommended dose is as follow Adults :
Two inhalations ( each 50 mcg ) three or four times a day .
In severe cases, dose during initial therapy may be doubled (600 – 800 mcg per day).
When improvement occurs, the dose should be adjusted according to response .
Children :
One or two inhalations (50 to 100 mcg) two, three or four times a day, depending on age and response .
The maximum daily dose should not exceed 20 inhalations (1 mg) for adults and 10 inhalations (0.5 mg) for children under 12 years of age
Adverse Reactions
Hoarseness , and dry mouth have occurred in few patients .
Bronchospasm , rash and localized infections with candida albicans or Aspergillus niger in the mouth and throat have been rarely reported
Contra Indications
Beclosone is contraindicated in patients with known hypersensitivity to any of its constituents .
Administration of the drug during pregnancy and lactation is not recommended .
This drug is contraindicated in the presence of hemorrhagic diathesis or a history of recurrent nasal bleeding .
Drug Interactions
None
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