Askine 300mg | Acetylsalicylic acid

Askine 300 mg

Acetylsalicylic acid 300 mg/tab. + Caffeine 10 mg/tab.

Company Name

Alexandria

Therapeutic Group

NON-NARCOTIC ANALGESICS

Pharmaceutical form

Tablet

Package

200 Tablets

Askine Indications

Mild to moderate pyrexia, antiplatelet (prophylaxis of cerebrovascular disease of myocardial infarction)

Askine Warning & Precautions

Reye’s syndrome: Owing to an association with Reye’s syndrome, it is recommended that aspirin containing preparations should no longer be given to children under 12 hears, unless specifically indicated e.g. for juvenile arthritis (still’s disease) it is important to advise families that aspirin is not a suitable medicine for children with minor illness. Concerning the harmful effect of acetyl salicylic acid (Aspirin) in the last three months of pregnancy due to the possibility of prolonging the period of pregnancy and the increased risk of antepartum and pospartum hemorrhage as well as the risk of bleeding tendency in the new born. Not to be used in high doses during the last three months of pregnancy.

Product Type

Human

Askine Dosage

Unless otherwise prescribed by the physician. Adults: 300-900 mg (1-3 tablets) every 4-6 hours when necessary; maximum 4 gm daily

Askine Adverse Reactions

Generally mild and infrequent but high incidence of gastrointestinal irritation with slight asymptomatic blood loss, increased bleeding time, bronchospasm and skin reactions in hypersensitive patients.

Askine Contra Indications

Children under 12 years and in breast feeding (Reye’s syndrome) gastrointestinal ulceration, haemophilia, not for treatment of gout.

Askine Drug Interactions

Other analgesics: avoid concomitant administration of other NSAIDs (increased side effects) Antacids and adsorbents: excretion of aspirin increased in alkaline urine; kaolin possibly reduces absorption Anticoagulants: increased risk of bleeding due to antiplatelet effect. Antiepileptics: enhancement of effect of phenytoin and valproate. Other antiplatelet drugs: increased risk of bleeding with clopidogrel and ticlopidine. Corticosteroids: increased risk of gastrointestinal bleeding and ulceration; corticosteroids reduce plasma salicylate concentration. Cytotoxics: reduced excretion of methotrexate (increased toxicity) Diuretics: antagonism of diuretic effect of spironolactone ; reduced excretion of acetazolamide (risk of toxicity). Leukotriene antagonists: asprin increases plasma concentration of zafirlukast. Metoclopramide and domperidone: metoclopramide enhances effect of asprin (increased rate of absorptio

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