Ampicillin 500mg Vials
Ampicillin sodium for injection B.P 2003 : Each vial contains Ampicillin (as sodium ) 500 mg.Company Name
CID
Pharmaceutical form
Vials
Package
Box contains 50 vials, each of 500 mg .
Indications
Ampicillin is indicated in the treatment of all infections caused by susceptible microorganisms mainly : • Respiratory tract infections : bronchitis , pharyngitis , uncomplicated commonly-acquired pneumonia , otitis media , and H-influenza infection . • Gastrointestinal tract infections : Enteritis , bacillary dysentery ,abdominal typhoid and paratyphoid • Genitourinary tract infections: Cystitis, pyelonephritis, prostatitis, urethritis and gonorrhea. • Listerial meningitis (in combination with other antibiotics).
Warning & Precautions
Caution is required when using Ampicillin in the following cases: • Known history of allergy. • Patients with cytomegalovirus infection since they are susceptible to ampicillin-induced skin rashes. • Patients with impaired renal function (dose should be reduced). • Patients with acute or chronic lymphocytic leukemia. • SGOT and SGPT should be measured during therapy to monitor for liver function abnormalities. N.B. Ampicillin is not known to be harmful during pregnancy or lactation.
Product Type
human
Dosage
By IM , IV injection or infusion: 500 mg every 4-6 hours. N.B. Children under 10 years should take half adult dose.
Adverse Reactions
- Hypersensitivity reactions like skin rashes and urticaria may occur. - Antibiotic-associated colitis may rarely occur.
Contra Indications
History of hypersensitivity to penicillins or cephalosporins .
Drug Interactions
• Allopurinol : increase risk of developing skin rashes. • Bacteriostatic antibiotics (I.e.: tetracycline, Erythromycin): diminish the bactericidal effect of Ampicillin. • Estrogen-containing oral contraceptives: Ampicillin may decrease the contraceptive effect. • Probenecid: blocks the renal tubular excretion of Ampicillin and prolong its blood level.
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