Amoclox 500
Amoxicillin trihydrate, equivalent to Amoxicillin anhydrous 250 mg Dicloxacillin sodium monohydrate, equivalent to Dicloxacillin 250 mg
Company Name
Memphis
Therapeutic Group
BROAD SPECT PENICILL ORAL
Pharmaceutical form
Capsule
Package
Box containing 16 capsules.
Indications
Amoclox capsules are indicated in the following conditions: - Infections of the ear , nose & throat due to Streptococcus species ( α & β hemolytic strains only ) , Streptococcus pneumoniae , Staphylococcus species or H. influenzae. - Infections of the genitourinary tract due to E.coli , P. mirabilis or E. faecalis.
- Infections of the skin & skin structures due to Streptococcus species (α & β hemolytic strains only ) , Staphylococcus species or E. coli.
- Infections of the lower respiratory tract due to Streptococcus species (α & β hemolytic strains only ) , Streptococcus pneumoniae , Staphylococcus species or H. influenzae.
- Gonorrhea , acute uncomplicated ano-genital & urethral infections due to N. gonorrhoeae ( males & females ).
- Biliary tract infections.
- Burn and wound infections .
- In the treatment of early symptoms of Lyme disease .
- Typhoid fever.
Warning & Precautions
- Serious hypersensitivity ( anaphylactic ) reactions have been reported in patients on penicillin therapy. - Before initiating therapy with amoclox, careful inquiry should be made concerning previous hypersensitivity reactions to penicillins , cephalosporins or other allergens . If an allergic reaction occurs , amoclox should be discontinued & appropriate therapy instituted. - Pseudomembranous colitis should be considered as a diagnosis in patients who present with diarrhea subsequent to the administration of amoclox ( due to amoxicillin content ). - Possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Amoclox should be discontinued - safety for use in pregnancy has not been established . -Penicillins are excreted in human milk . Amoclox use by nursing mothers may lead to sensitization of infants , thus, caution should be exercised .
Product Type
Human
Dosage
For adults :one capsule every 8 hours .
Adverse Reactions
- Gastrointestinal : nausea , vomiting , diarrhea & hemorrhagic/ pseudomembranous colitis. - Hypersensitivity reactions : pruritus , urticaria , skin rashes.
Contra Indications
A history of allergic reaction to any of the penicillins is a contraindication
Drug Interactions
• Probenecid decreases the renal tubular secretion of amoclox & may result in increased &prolonged levels of amoclox . • Chloramphenicol ,macrolides ,sulfonamides & tetracyclines may interfere with the bactericidal effects of amoclox .
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