Tuesday, July 16, 2013

Neostigmine Bromide | Neostigmine

Neostigmine Bromide | Neostigmine

Neostigmine

Neostigmine Bromide 15 mg

Company Name

Memphis

Therapeutic Group

ALL OTHER CNS DRUGS

Pharmaceutical form

Tablet

Package

Box containing 20 tablets

Indications

Neostigmine is indicated for the symptomatic treatment of myasthenia gravis.

Warning & Precautions

Neostigmine should be used with caution: - in patients with epilepsy, bronchial asthma, bradycardia, hyperthyroidism, peptic ulcer, recent coronary occlusion, vagotonia and cardiac arrhythmias. - when administered with anticholinergic drugs, in order to avoid reduction of intestinal motility. -Pediatric use: Safety and effectiveness in children have not been established. -Either discontinue nursing or discontinue the drug taking into account the importance of the drug to the mother. -Neostigmine should be given to a pregnant woman only if clearly needed.

Product Type

Human

Dosage
Initial : 15 mg every 3 - 4 hours, the dose and frequency of administration being adjusted as necessary. Maintenance: 150 mg administered over a twenty-four hour period, the intervals between doses being determined by response of the patient.

Adverse Reactions

Some of the following side effects may occur in some cases: Salivation, allergic reactions, convulsions, cardiac arrhythmias, increased bronchial secretions, fasciculation, bowel cramps, diarrhea, anaphylaxis, loss of consciousness, drowsiness, headache, dysarthria, miosis and visual changes, rash, nausea, emesis, flatulence, increased peristalsis, urinary frequency, muscle cramps and spasms, arthralgia, diaphoresis, flushing and weakness.

Contra Indications

Neostigmine is contraindicated in: -Patients with peritonitis or mechanical obstruction of the intestinal or urinary tract. -Patients with known hypersensitivity to the drug

Drug Interactions

-Streptomycin, neomycin and kanamycin have a mild but definite non-depolarizing blocking action which may accentuate neuromuscular block. -Local and some general anesthetics and antiarrhythmic agents that interfere with neuromuscular transmission should be used cautiously
5 EgyDrug Index: Neostigmine Bromide | Neostigmine Neostigmine Neostigmine Bromide 15 mg Company Name Memphis Therapeutic Group ALL OTHER CNS DRUGS Pharmaceutical form ...

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