 |
| Mucosolvan | Ambroxol |
Mucosolvan 15 mg/Ampoule
Each ampoule (2 ml) contains 15 mg Ambroxol HclCompany Name
CID/Boehringer - EgyptTherapeutic Group
EXPECTORANTSPharmaceutical form
AmpoulePackage
Box of 10 ampoules of 2 ml.Mucosolvan /Ambroxol Indications
- Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport, such as acute exacerbation of chronic bronchitis, bronchiectasis, asthmoid bronchitis and bronchial asthma. - In pre- and post operative treatment. - The ampoules are especially suitable for prevention of the pulmonary complications in intensive medicine.Mucosolvan /Ambroxol Warning & Precautions
- Preclinical studies as well as extensive clinical experience after the 28th week have shown no evidence of ill-effects during pregnancy. Nonetheless, the usual precautions regarding the use of drugs during pregnancy, especially during the first trimester, should be observed. - The drug enters breast milk, but is not likely to affect the infant when therapeutic doses are used. - Mucosolvan solution contains the preservative benzalkonium chloride. It has been reported that this preservative may cause bronchoconstriction on some patients with hyper-reactive airways.Product Type
human
Mucosolvan /Ambroxol Dosage
- Mucosolvan ampoules: Adults: In general, good results have been obtained with the administration of 1 ampoule 2 or 3 times daily. In severe cases the single dose may be increased to 2 ampoules. Administration should be IV or IM, although SC application is also well tolerated. Children over 5 years: 1 ampoule 2-3 times daily. Children 2 - 5 years : ½ ampoule 3 times daily. Children under 2 years: ½ ampoule twice daily. Administration for children should be IV although IM application is also well tolerated. N.B. - If the IV administration is too rapid, headache, pain in the legs and exhaustion may occur. - The solution can also be administered as a drip infusion together with glucose, laevulose, saline or Ringer's solution . - Mucosolvan (pH 5.0) should not be mixed with other solution with a pH greater than 6.3 as precipitation of the free Mucosolvan base can result due to the pH increase. - The combination of parenteral and inhalative therapy with Mucosolvan has proved effective as intensive therapy. Therapy can then be continued with oral dosage forms .Mucosolvan /Ambroxol Adverse Reactions
Mucosolvan is generally well tolerated. rare cases of hypersensitivity reactions have been reported and in single cases acute anaphylactic-type signs of shock. The following signs have been observed: skin reactions and/or mucosal reactions, swelling of the face, dyspnea, rise in temperature with chills, gastrointestinal complaints have been reported in very rare cases.Mucosolvan /Ambroxol Contra Indications
Known hypersensitivity to ambroxol.Mucosolvan /Ambroxol Drug Interactions
Administration of ambroxol together with antibiotics (amoxicillin, cefuroxime, erythromycin and doxycycline) leads to antibiotic concentration in lung tissue. No clinically relevant unfavorable interaction with other medication have been reported.
Mucosolvan 30 mg/Tablet
Each tablet contains 30 mg Ambroxol HCl
Company Name
CID/Boehringer
Pharmaceutical form
Tablet
Package
Box of 20 tablets (2 strips each contains 10 tablets).Indications
- Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport, such as acute exacerbation of chronic bronchitis, bronchiectasis, asthmoid bronchitis and bronchial asthma. - In pre- and post operative treatment.Warning & Precautions
- Preclinical studies as well as extensive clinical experience after the 28th week have shown no evidence of ill-effects during pregnancy. Nonetheless, the usual precautions regarding the use of drugs during pregnancy, especially during the first trimester, should be observed. - The drug enters breast milk, but is not likely to affect the infant when therapeutic doses are used. - Mucosolvan solution contains the preservative benzalkonium chloride. It has been reported that this preservative may cause bronchoconstriction on some patients with hyper-reactive airways.Product Type
humanDosage
- Mucosolvan tablets: Adults: 1 tablet 3 times daily. In long-term therapy, the dose may be reduced to twice daily. The tablets should be taken after meals with liquid.Adverse Reactions
Mucosolvan is generally well tolerated. rare cases of hypersensitivity reactions have been reported and in single cases acute anaphylactic-type signs of shock. The following signs have been observed: skin reactions and/or mucosal reactions, swelling of the face, dyspnea, rise in temperature with chills, gastrointestinal complaints have been reported in very rare cases.Contra Indications
Known hypersensitivity to ambroxol.Drug Interactions
Administration of ambroxol together with antibiotics (amoxicillin, cefuroxime, erythromycin and doxycycline) leads to antibiotic concentration in lung tissue. No clinically relevant unfavorable interaction with other medication have been reported.
Mucosolvan Drops
Each 2 ml contains 15 mg. Ambroxol HclCompany Name
CID/Boehringer
Therapeutic Group
EXPECTORANTS
Pharmaceutical form
Drops
Package
Glass bottle of 40 ml solution.
Indications
- Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport, such as acute exacerbation of chronic bronchitis, bronchiectasis, asthmoid bronchitis and bronchial asthma. - In pre- and post operative treatment.
Warning & Precautions
- Preclinical studies as well as extensive clinical experience after the 28th week have shown no evidence of ill-effects during pregnancy. Nonetheless, the usual precautions regarding the use of drugs during pregnancy, especially during the first trimester, should be observed. - The drug enters breast milk, but is not likely to affect the infant when therapeutic doses are used. - Mucosolvan solution contains the preservative benzalkonium chloride. It has been reported that this preservative may cause bronchoconstriction on some patients with hyper-reactive airways.
Product Type
human
Dosage
-The recommendations for children are based on a total daily dose of 1.2-1.6 mg/kg b.wt. unless otherwise pescribed. Mucosolvan solution (15mg/2ml) for oral or inhalation use: Oral (1 ml = 25 drops): Adults: at the initiation of treatment 4 ml 3 times daily. In long term treatment, the dose may be reduced to 2 ml 3 times daily . Children over 5 years: 2ml (50 drops) 2-3 times daily. Children 2-5 years: 1ml (25 drops) 3 times daily. Children under 2 years: 1ml (25 drops) twice daily. The drops should be taken with meals diluted with tea, fruit juice, milk or water . Inhalation: Adult and Children over 5 years: 1-2 inhalations of 2-3 ml solution daily. Children under 5 years: 1-2 inhalations of 2 ml solution daily . N.B. - Should only one inhalation per day be possible, a sustained action can be achieved by the supplementary administration of tablets or liquid . - Mucosolvan inhalant solution can be used in all modern inhalation devices (excluding steam inhalers). It is miscible with physiological saline solution and may be diluted 1:1 in order to obtain optimal moisturisation of the respiratory air in a respirator. - Since deep inhalation may provoke a cough impulse, the patient should breathe normally during the inhalation treatment. - Warming the solution to body temperature before inhalation is recommended for sensitive patients. - Patients with bronchial asthma should use a bronchospasmolytic before commencing inhalation.
Adverse Reactions
Mucosolvan is generally well tolerated. rare cases of hypersensitivity reactions have been reported and in single cases acute anaphylactic-type signs of shock. The following signs have been observed: skin reactions and/or mucosal reactions, swelling of the face, dyspnea, rise in temperature with chills, gastrointestinal complaints have been reported in very rare cases.
Contra Indications
Known hypersensitivity to ambroxol.
Drug Interactions
Administration of ambroxol together with antibiotics (amoxicillin, cefuroxime, erythromycin and doxycycline) leads to antibiotic concentration in lung tissue. No clinically relevant unfavorable interaction with other medication have been reported.
Mucosolvan Syrup
Company Name
CID/Boehringer
Therapeutic Group
EXPECTORANTS
Pharmaceutical form
Syrup
Package
Glass bottle of 100 ml liquid.
Indications
- Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport, such as acute exacerbation of chronic bronchitis, bronchiectasis, asthmoid bronchitis and bronchial asthma. - In pre- and post operative treatment.
Warning & Precautions
- Preclinical studies as well as extensive clinical experience after the 28th week have shown no evidence of ill-effects during pregnancy. Nonetheless, the usual precautions regarding the use of drugs during pregnancy, especially during the first trimester, should be observed. - The drug enters breast milk, but is not likely to affect the infant when therapeutic doses are used. - Mucosolvan solution contains the preservative benzalkonium chloride. It has been reported that this preservative may cause bronchoconstriction on some patients with hyper-reactive airways.
Product Type
human
Dosage
The recommendations for children are based on a total daily dose of 1.2-1.6 mg/kg b.wt. unless otherwise prescribed : - Mucosolvan liquid (15 mg / 5 ml): Adults and children over 12 years: 10 ml ( 2 measuring cups ) 3 times daily for the first 2-3 days. Later, 5 ml (1 measuring cup) 3 times daily . Children 5 - 12 years: 5 ml (1 measuring cup) 2-3 times daily . Children 2 - 5 years: 2.5 ml ( ½ measuring cup) 3 times daily Children under 2 years : 2.5 ml ( ½ measuring cup) twice daily . The above regimen are suitable for the therapy of acute respiratory tract disorders and for the initial treatment of chronic conditions up to 14 days. In longer treatment the dose can be halved. Mucosolvan liquid should be taken at meal times .
Adverse Reactions
Mucosolvan is generally well tolerated. rare cases of hypersensitivity reactions have been reported and in single cases acute anaphylactic-type signs of shock. The following signs have been observed: skin reactions and/or mucosal reactions, swelling of the face, dyspnea, rise in temperature with chills, gastrointestinal complaints have been reported in very rare cases.
Contra Indications
Known hypersensitivity to ambroxol.
Drug Interactions
Administration of ambroxol together with antibiotics (amoxicillin, cefuroxime, erythromycin and doxycycline) leads to antibiotic concentration in lung tissue. No clinically relevant unfavorable interaction with other medication have been reported.
No comments:
Post a Comment