Azethromycin
Azithromycin(as dihydrate) 250 mg
Company Name
Misr
Pharmaceutical form
capsules
Indications
*Acute bacterial exacerbations of chronic obstructive pulmonary disease *Community aquired pneumonia*Pharengitis and tonsilitis*Uncomplicated skin and skin structure infections *Urethritis and cervicitis *Genital ulcer disease
Warning & Precautions
Because azithromycin is principally eliminated via the liver ,caution should be exercised when azithromycin is administered to patients with impaired hepatic function. *Patients should be cautioned to take azithromycin at least one hour prior to a meal or at least two hours after a meal & should not be taken with food. *Patients should discontinue azithromycin immediately and contact any physician if any signs of an allergic reaction occurs. WARNINGS: -In the treatment of pneumonia ,azithromycin should not be used in patients who are judged to be inappropriate for oral therapy because of moderate to severe illness or risk factors such as any of the following conditions : *Patients with cystic fibrosis. * Patients with nosocomially acquired infections. *Patients with known or suspected bacteremia. *Patients requiring hospitalization, elderly or debilitated patients ,or patients with significant underlying health problems that may compromise their ability to respond to their illness. -Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia.
Product Type
Human
Dosage
IN ADULTS: -Treatment of genital ulcer disease due to Haemophilus ducreyi ,non-gonococcal urethritis & cervicitis due to Chlamydia trachomatis is a single 1gm dose. -Treatment of urethritis & cervicitis due to Neisseria gonorrhea is a single 2gm dose. -For treatment of all other infections the dose is 500mg once daily for 3 days. IN CHILDREN: -In acute otitis media and acquired pneumonia ,the dose is 10mg/kg as a single dose on the first day (not to exceed 500mg/day) followed by 5mg/kg on day 2 through 5 (not to exceed 250mg/day). -Treatment of paryngitis /tonsillitis ,the dose is 12mg/kg once daily for 5 days (not to exceed 500mg/day).
Adverse Reactions
Nauseea, vomiting,diarrhea or abdominal pain Rare : Palpitations , chest pain, dyspepsia , flatulance, vomiting , monilia, dizziness , headache , vertigo , fatigue , rash ,angioedema & photosenisitivity
Contra Indications
. Hypersensitivity to azithromycin , erythromycin or any macrolide antibiotic
Drug Interactions
Patients should be cautioned not to take aluminum and magnesium containing antacids simultaneously with azithromycin.
No comments:
Post a Comment