EgyDrug Index

Monday, October 7, 2013

Bekcium 250 mg | Calcium dobesilate

Bekcium 250 mg

Calcium dobesilate 250 mg/cap.

Company Name

Alexandria

Therapeutic Group

SYSTEMIC VASOPROTECTIVES

Pharmaceutical form

Capsule

Package

30 or 1000 Capsules

Indications

In microangiopathies, in particular diabetic retinopathy. Clinical signs of chronic venous insufficiency in the lower limbs (pain, cramps, paresthesia), as adjuvant in the treatment of superficial thrombophlebitis, Post-thrombotic syndrome , oedema and stasis dermatosis . Microcirculation disorders of arteriovenous origin and haemorrhoidal syndrome.

Warning & Precautions

Product Type

Human

Dosage

As directed by the physician or as follows : 2-3 capsules of Bekcium 250 to be taken with the main meals. Treatment duration, which is generally between a few weeks and several months, depends on the doctor’s opinion .

Adverse Reactions

In general Bekcium is well tolerated during treatment . Gastrointestinal disorders , nausea , diarrhoea, skin reactions have been reported. But in most cases no discontinuation of the drug is required.

Contra Indications

Drug Interactions

No interaction is known up to now

Bedoxine tablets

Bedoxine

Each tablet contains: Pyridoxine Hcl 250 mg Thiamine Hcl 250 mg

Company Name

CID

Pharmaceutical form

Tablets

Package

Box of 20 tablets ( 2 strips of 10 tablets each).

Indications

* Treatment of vitamin B1 or B6 deficiency states which may include: - Beriberi: due to vitamin B1 deficiency which may be related to cardiovascular.or nervous system. - Vitamin B6 deficiency either due to inadequate diet or isoniazid therapy or use of oral contraceptives. - Sideroblastic anemia (idiopathic, acquired or hereditary). * Peripheral neuritis. * Nausea and vomiting of pregnancy. * High doses are given in some metabolic disorder such as hyperoxaluria.

Warning & Precautions

• Used cautiously in patient with hypersensitivity to any of drug components. • Bedoxine should be used during pregnancy & lactation only if clearly needed.

Product Type
human

Dosage
1-3 tablets daily

Adverse Reactions
Paresthesia, somnolence, and low serum folic acid have been reported.

Contra Indications
None known.

Drug Interactions
Pyridoxine supplements should not be given to patients receiving levodopa, because the action of the latter is antagonized by pyridoxine. N.B. Bedoxine can be used concurrently in patient receiving a preparation containing both levodopa and carbidopa.

Beco-C syrup

ThiamineHCL 100mg, Riboflavine 30mg, Pyridoxine 20mg, Nicotinamide 240mg, Calcium pantothenate 20mg

Company Name

Misr

Therapeutic Group

VITAMIN B COMPLEX + VIT C

Pharmaceutical form

syrup

Package

Bottles of 60 ml.Bottles of 125 ml.

Indications

Conditions where vitamin B complex & vitamin C are needed as in: - Inadequate intake. - Increased requirement e.g. during periods of growth , pregnancy, lactation, infections, fevers ,wasting diseases , exposure to cold or other stressconditions (such as trauma , burns, surgery ,increased physical or mentalwork, treatment with certain drugs as antimicrobials or estrogens(including oral contraceptives), - Oral diseases: cheilosis , aphthous and other types of stomatitis.

Warning & Precautions

Patients should be instructed not to lie down immediately after taking a dose of vitamin O13 because prolonged contact of ascorbic acid with esophageal mucosa may cause localized esophagitis. Vitamin C may cause false positive results for urine glucose with copper sulphate reduction test with high doses , and may cause negative results when glucose oxidase methods are used. Intense yellow discoloration of urine may occur especially with high doses due to excretion of vitamin B Chronic administration of high doses of vitamin B6 (e.g 2gm or more daily for several months) has led to sensory neuropathy associated with ataxia & numbness of hands & feet. Patients with gallbladder disease, history of jaundice or liver disease should be monitered if there are persistent unexplained elevations of transaminases more than 3 times the upper limit of normal or if the LFTs are associated with fever , nausea& /or malaise , Niacin should be discontinued.

Product Type

Human

Dosage

Children : 1/2 – 1 teaspoonful two to three times daily .K13 Adults: 2 teaspoonfuls t.d.s.K13

Adverse Reactions

very rarely conditions of hypersensitivity (to vitamin B1mainly), angioneurotic edema, pulmonary edema, nausea ,vomiting ,heart burn, abdominal cramps, fatigue ,flushing, insomnia.

Contra Indications

It is contraindicated in patients with known hypersensitivity to any ingredient in the formulation. Patients with active liver disease ,peptic ulcer disease , hyperuricemia with gouty arthritis ,uncontrolled hyperglycemia or severe hypotension.

Drug Interactions

For vitamin B complex: Vit B6 increases the peripheral metabolism of levodopa . when levodopa iscombined with carpidopa , this effect is prevented. - Patients taking estrogens e.g. oral contraceptives have higher vit B6requirements. - For vitamin C - Salicylates inhibit uptake of Vitamin C into leukocytes & platelets. - The excretion of weak acid or weak base drugs may be decreased or increasedrespectively because Vit C is a urinary acidifier in large doses - For Nicotinamide: - Postural hypotension may occur when Niacin is administered with vasoactive drugs or ganglionic blocking agents. - Dosage adjustment of Insulin or oral antihyperglycemic therapy may be required in diabetics because Niacin can cause hyperglycemia.

Beco VITAMIN B COMPLEX

Beco

ThiamineHCL 5mg, Riboflavine 2mg, Pyridoxine 0.5mg, Nicotinamide 30mg, Calcium pantothenate 1mg, cyanocobalamine HCL 1 mcg.

Company Name

Misr

Therapeutic Group

VITAMIN B COMPLEX PLAIN

Pharmaceutical form

tablets

Package

boxes of 10 tablets

Indications

Gross Vitamin deficencies: e.g. beri-beri, pellagra

Warning & Precautions

due to ecretion of vit. B2, intense yellow discolaratin of urine may occur specially with high doses

Product Type

Human

Dosage

1-2 tablets two or three times daily. 1 tablet two or three times daily.

Adverse Reactions

hypersensitivity reactions may occur

Contra Indications

hypersensitivity reactions to any of components

Drug Interactions

vit B6 in doses of 5 mg or more daily may inhibit the action of L-dopa but not decarboxylase inhibitors

Beclozone | Beclomethasone dipropionate

Beclozone
Beclomethasone dipropionate 0.025 g / 100 g

Company Name
Memphis

Therapeutic Group
TOP CORTICOSTEROIDS PLAIN

Pharmaceutical form
Cream

Package
Tubes containing 20 g of the cream .

Indications
BECLOZONE cream contains beclomethasone dipropionate which is a corticosteroid for topical application with an action which is more potent than that of hydrocortisone. It has marked vasoconstrictor and anti-inflammatory activity.
It may be used under an occlusive dressing to obtain a more intensive effect. The preparation is useful in various skin disorders as Acne, napkin dermatitis, Alopecia, Aphthous ulcers and some forms of psoriasis.

Warning & Precautions
The cream should not be used on infected skin without the simultaneous application of a suitable antibacterial agent. - In the case of napkin rash, topical application should include antibacterial and/or fungicidal agents usually in association with BECLOZONE cream. - More potent topical application of BECLOZONE cream should not be applied to the skin of infants because of the real danger of dermal atrophy.

Product Type
Human

Dosage

The cream should be applied sparingly to the affected area.
The application may be with or without conventional dressings or under an occlusive dressing, if large areas are treated under occlusive dressing, sufficient amount of the drug may be absorbed to give rise to systemic effects.

Adverse Reactions

NA

Contra Indications

NA

Drug Interactions
NA

Beclosone Non CFC | Beclomethasone dipropionate

Beclosone Non CFC

Beclomethasone dipropionate

Company Name

ADCO

Therapeutic Group

CORTICOIDS INHALANTS

Pharmaceutical form

Inhaler

Package

Canister of 200 inhalations

Indications

A- Oral

Beclomethasone dipropionate is indicated for the control of asthma , particularly in those patients who have been dependent upon either systemically administered corticosteroids or ACTH or who require frequent use of bronchodilating agents .

It is not recommended for the treatment of status asthmaticus .Inhalation of beclomethasone dipropionate is particularly indicated in the following patients :

1- Patients whose asthmatic condition is expected to require long–term maintenance therapy .

2- The majority of severe asthmatics who are dependent on systemic corticosteroids or ACTH .

3- Patients who are receiving intermittent courses of systemic corticosteroids .

4- Patients whose symptoms of bronchial asthma have become less responsive to bronchodilators and require progressively higher doses for relief .

5- Patients for whom bronchodilating compounds are relatively contraindicated such as cardiac patients, etc.

6- Patients whose symptoms are not adequately controlled by combined therapy using bronchodilators with disodium cromoglycate 7- Children with severe asthma; effective control of symptoms has been achieved without the retardation of growth commonly associated with systemic administration of corticosteroids .

Resumption of growth has been reported in children transferred from systemic corticosteroids to beclomethasone dipropionate therapy Pituitary – adrenal suppression resulting from prolonged use of systemic corticosteroids or ACTH , tachycardia and palpitation associated with bronchodilators and gastrointestinal intolerance of aminophylline – like agents can be substantially reduced or eliminated when beclomethasone dipropionate for oral inhalation is prescribed .

B- Intra-Nasal

Beclomethasone dipropionate aerosol , intra-nasaly , is indicated for the treatment of scasonal and perennial allergic rhinitis and vasomotor rhinitis . It may also be used as adjunctive therapy in the medical treatment of nasal polyps .

Warning & Precautions

Beclosone is not to be regarded as a bronchodilator and is not recommended for rapid relief of bronchospasm . Patients should be instructed to contact their physicians immediately when asthmatic episodes are not responsive to bronchodilators during treatment with Beclosone , during such episodes , patients may require systemic corticosteroid therapy . Do not exceed the prescribed dose Beclosone inhaler should be used with caution in patients with active or quiescent tuberculous infections of the respiratory tract .

Product Type

Human

Dosage

For Oral Inhalation :

The usual recommended dose is as follow Adults :

Two inhalations ( each 50 mcg ) three or four times a day .

In severe cases, dose during initial therapy may be doubled (600 – 800 mcg per day).

When improvement occurs, the dose should be adjusted according to response .

Children :

One or two inhalations (50 to 100 mcg) two, three or four times a day, depending on age and response .

The maximum daily dose should not exceed 20 inhalations (1 mg) for adults and 10 inhalations (0.5 mg) for children under 12 years of age

Adverse Reactions

Hoarseness , and dry mouth have occurred in few patients .

Bronchospasm , rash and localized infections with candida albicans or Aspergillus niger in the mouth and throat have been rarely reported

Contra Indications

Beclosone is contraindicated in patients with known hypersensitivity to any of its constituents .

Administration of the drug during pregnancy and lactation is not recommended .

This drug is contraindicated in the presence of hemorrhagic diathesis or a history of recurrent nasal bleeding .

Drug Interactions

None

Beauty gel

Each 100 gm contains: Hydroquinone 2.0 g. Retinoic acid 0.05 g.

Company Name

CID

Therapeutic Group
OTHER DERMATOLOGICAL PREP

Pharmaceutical form
Gel

Package
Tube of 30 g.

Indications

• Beauty Gel is mainly used in cases of localised hyperpigmentation of the following : - Melasma ( cholasma that accompany frequency of gonodal disturbances) - Hyperpigmentation that follows burns. - Post inflammatory hyperpigmentations. • Hyperpigmentation that follows contact with essential oil (Eau de cologne). • Ephelis ( Freckling) . • Hyperpigmentation following prolonged sun exposure .

Warning & Precautions

Warnings - Must be used under medical supervision. - Not to be used in children younger than 12 years of age. - Treatment should be limited to relatively small area of the body , not more than 10 %. - Not to be used in pregnancy. - Duration of treatment should be limited to 2 months with maximum of 4 months. - Beauty Gel is intended for night time use only since it contains no sun protecting agent. - Beauty Gel should not be administered if the patient is also taking drugs known to be photo sensitizers (e.g. thiazides , tetracyclines , fluroquinolones , phenothiazines, sulphonamides) because of the possibility of augmented phototoxicity. - Patients with sunburn should be advised not to use beauty gel until fully recovery. - Patients with inherent sensitivity to sunlight or who may have considerable sun exposure due to their occupation should exercise particular caution when using Beauty Gel . - If no bleaching or lightening effect is noted after 2 months of treatment, use of medicine should be discontinued . - After clearing and during maintenance therapy, UV exposure should be avoided. - This product contains sodium metabisulphite which may cause serious allergic type reaction in certain susceptible persons . Precautions : Beauty Gel is relatively nontoxic but induces mild sensitivity in very few cases such as after hair epilation or shaving as well as in sweat rashes. It produces irritation to mucous membranes , so it should not be used near the eyes, angles of the nose. For these reasons sensitivity test should be done before use by rubbing a small area of the skin with the gel, if there is no rash the test is negative and the treatment is safely continued. If skin rashes appeared the treatment is stopped immediately.

Product Type

human

Dosage

Beauty Gel is rubbed on hyperpigmented areas once or twice at night. Exposure to sun light should be avoided after application of the gel.

Adverse Reactions

- Drying and fissures of paranasal and infra orbital areas . - Erythema , stinging, peeling , dry skin and pruritus .

Contra Indications

- Sensitivity reactions to the components of the preparation . - Patients older than 50 years of age.

Drug Interactions

- Skin irritation may occur when beauty gel is used with medicated or abrasive soaps and cleaners, shampoos, and cosmetics products that have strong drying effects and products with high concentrations of alcohol, astringents, spices or lime. - Permanent wave solution, electrolytes, hair depilatories or waxes and products that may irritate the skin should be used with caution in patients being treated with products that contain retinoic acid because it may increase irritation .

Baclofen 10 mg

Baclofen .10 mg B.P98

Baclofen 10 mg

Company Name

Misr/Delta

Pharmaceutical form

tablets

Package

Box of 10&20 tab

Indications

Spasticity of the skeletal muscles in multiple sclerosis. * Spastic conditions occurring in spinal cord diseases of infectious, degenerative, traumatic, neoplastic or unknown origin as in spastic spinal paralysis, amyotrophic lateral sclerosis, syringomyelia, transverse myelitis, traumatic paraplegia or paraparesis and compression of the spinal cord.

Warning & Precautions

Uses in pregnancy only if benefit clearly justifies the potential risk to the fetus. * Not used for lactating mother because it excreated in the breast milk. Abrupt discontinuation of treatment should be avoided. *It has no significant benefit for patients with stroke. *It is not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders, parkinsonism, cerebral palsy or trauma induced cerebral lesions.

Product Type

Human

Dosage

Adults: *Dosage is started with 5 mg daily 3 times daily then raised at 3-day intervals by 5mg increments every dose until the desired response is achieved . Optimum dosage is 30 mg to 75 mg daily. *In hospitalised patients daily dosages of 80-100 mg may be necessary. *In patients with impaired renal function or undergoing chronic haemodialysis, a particulary low dosage of about 5mg daily should be selected. *In elderly patients or in patients with spastic states of cerebral origin, the patient should be kept under appropriate surveillance. Children *Children aged 6-10 years : 30-60 mg/daily * In children over 10 years of age, a maximum dosage of 2.5 mg/kg body wt. may be given *Treatment is started with 2.5 mg 4 times daily, then raised cautiously at 3 days intervals until it becomes sufficient for individual child requirement . Paediatrics Dosage range is 0.75-2 mg/kg body weight

Adverse Reactions

With low doses , as recommended for the relief of painful muscle spasms ,side effects are rare and usually mild and transient , including : Constipation , nausea , urinary frequency , headache , insomnia, tinnitus, hypotension , drawsiness, dizziness, sedation, fatigue , weakness, rash, pruritus and ankle edema , muscle pain ,tremors ,epileptic seizures , slurred speech , palpitations , chest pain , dry mouth and respiratory depression may occur. In laboratory tests : increase liver enzyme level, increase level of alkaline phosphatase and increase of blood sugar.

Contra Indications

Should not be given to individuals with a history of baclofen sensitivity. Patients suffering from psychotic disorders, schizophrenia or confusional states should be treated cautiously with baclofen. Also used with caution in patients with a history of peptic ulcers, those suffering from cerebrovascular diseases or from respiratory, hepatic renal failure or prophyria. *Caution is excercised in patients with pre-existing hypertonic sphincter, epilepsy, automobiles or other dangerous machinery.

Drug Interactions

Sedation may occur if taken with CNS depressants or with alcohol. *During current treatment with tricyclic antidepressants, the effect of baclofen may be potentiated resulting in muscular hypotonia. * Concomitant treatment of baclofen with antihypertensives are likely to increase the fall in blood pressure. Also reports of mental confusion, hallucinations and agitation may occur in patients with Parkinson's disease receiving levodopa plus carbidopa

Baby-tal

Baby-tal

Phenobarbital 6 mg. pipenzolate bromide 4 mg.

Company Name
El Kahira

Therapeutic Group
ANTISPASM\ATARACITC COMBS

Pharmaceutical form
Bottles

Package
Bottle of 15 ml with a dropper

Indications
Gastrointestinal colics, Cardiospasm and pylorospasm ,Vomiting. and Excessive regurgitation.

Warning & Precautions
None.

Product Type
HUMAN

Dosage

To be given directly into the mouth ,or with water, milk, or fruit juices, 15 minutes before feeding. Infants up to 1 year: 8 -16 drops 2 times daily.Children over to year: 16-32 drops 4 to 5 times daily.

Adverse Reactions

May occur only with high doses: Dryness of the mouth,constipation,excessive sedation and rarely urine retention.

Contra Indications

Gastrointestinal obstruction. Hypersensitivity to any of the components.

Drug Interactions

The anticholinergic action of pipenzolate may be potentiated by other anti-cholinergics and antihistamines the sedative effect of pipenzolate may be potentiated by other central nervous system depressants.

Azethromycin

Azithromycin(as dihydrate) 250 mg

Company Name

Misr

Pharmaceutical form

capsules

Indications

*Acute bacterial exacerbations of chronic obstructive pulmonary disease *Community aquired pneumonia*Pharengitis and tonsilitis*Uncomplicated skin and skin structure infections *Urethritis and cervicitis *Genital ulcer disease

Warning & Precautions

Because azithromycin is principally eliminated via the liver ,caution should be exercised when azithromycin is administered to patients with impaired hepatic function. *Patients should be cautioned to take azithromycin at least one hour prior to a meal or at least two hours after a meal & should not be taken with food. *Patients should discontinue azithromycin immediately and contact any physician if any signs of an allergic reaction occurs. WARNINGS: -In the treatment of pneumonia ,azithromycin should not be used in patients who are judged to be inappropriate for oral therapy because of moderate to severe illness or risk factors such as any of the following conditions : *Patients with cystic fibrosis. * Patients with nosocomially acquired infections. *Patients with known or suspected bacteremia. *Patients requiring hospitalization, elderly or debilitated patients ,or patients with significant underlying health problems that may compromise their ability to respond to their illness. -Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia.

Product Type

Human

Dosage

IN ADULTS: -Treatment of genital ulcer disease due to Haemophilus ducreyi ,non-gonococcal urethritis & cervicitis due to Chlamydia trachomatis is a single 1gm dose. -Treatment of urethritis & cervicitis due to Neisseria gonorrhea is a single 2gm dose. -For treatment of all other infections the dose is 500mg once daily for 3 days. IN CHILDREN: -In acute otitis media and acquired pneumonia ,the dose is 10mg/kg as a single dose on the first day (not to exceed 500mg/day) followed by 5mg/kg on day 2 through 5 (not to exceed 250mg/day). -Treatment of paryngitis /tonsillitis ,the dose is 12mg/kg once daily for 5 days (not to exceed 500mg/day).

Adverse Reactions

Nauseea, vomiting,diarrhea or abdominal pain Rare : Palpitations , chest pain, dyspepsia , flatulance, vomiting , monilia, dizziness , headache , vertigo , fatigue , rash ,angioedema & photosenisitivity

Contra Indications

. Hypersensitivity to azithromycin , erythromycin or any macrolide antibiotic

Drug Interactions

Patients should be cautioned not to take aluminum and magnesium containing antacids simultaneously with azithromycin.

A-VITON | VIT.A PALMITATE

A-VITON

VIT.A PALMITATE 50000 T.U

Company Name
El Kahira

Pharmaceutical form
Capsule

Package
of 20capsules.

Indications
Prophylaxis and treatment of signs of vitamin A deficiency, In skin diseases. and In thyrotoxicosis.

Warning & Precautions
Patients receiving high dosage over a prolonged period should be watched for signs of hypervitaminosis.

Product Type
HUMAN

Dosage
1-2 capsules during or after meals daily.

Adverse Reactions
Chronic Hypervitaminosis A,may occur when daily doses higher tham 25.000 I.U. are given for prolonged period.

Contra Indications
Hyper sensitivity to Vit.A Renal impairement. Oral administration in malabsorption.

Drug Interactions
Concomitant administration of mineral oils for prolonged periods impairs intestinal absorption of Vit.A

Atropine 1mg/1ml | Atropine sulphate

Atropine 1mg/1ml

Each ampoule (1 ml) contains: Atropine sulphate 1 mg

Company Name

CID

Therapeutic Group

ANTISPASM+ANTICHOL PLAIN

Pharmaceutical form

Ampoule

Package

Box of 100 ampoules .

Indications

- In preanesthetic medication to reduce or prevent salivary and bronchial secretions. - To restore cardiac rate and arterial pressure during anesthesia. - To overcome severe bradycardia and syncope due to hyperactive carotid sinus reflex. - To lessen the degree of atrioventricular heart block when increased vagal tone which is a major factor in the conduction defects. - In acute arrhythmias and in cardiopulmonary resuscitation to block vagal activity. - Before or with neostigmine to prevent bradycardia, excessive salivation and other muscarinic action of neostigmine. - Due to its antimuscarinic action, atropine can be used to prevent bradycardia and hypotension associated with agents such as halothane, propofol and suxamethonium. - As an antidote in cardiovascular collapse resulting from the improper use of choline ester drug. - In the treatment of poisoning from organophosphorous insecticides and in the rapid type of mushroom poisoning due to presence of the muscarine alkaloid. - Sympathomimetic relief of GIT disorders characterized by smooth muscles spasm including irritable bowel syndrome and diverticular disease. - Other indications : atropine can be used alone or adjuvant in the treatment of bronchial asthma and anoxic seizures.

Warning & Precautions

Atropine should be used with caution in the following cases:- - Down's syndrome, children, elderly , chronic lung diseases and in myasthenia gravis . - In cardiovascular disorders such as tachycardia, hypertension or myocardial infarction. - Diarrhea, gastro esophageal reflux disease and ulcerative colitis . N.B.: Do not administer unless the solution is clear and seal is intact. Pregnancy: Atropine should be given to pregnant women only if clearly needed.

Product Type

human

Dosage

Adults: - Premedication: ( 0.3 - 0.6 )mg either I.V. immediately before induction of anesthesia or I.M. ( 30 – 60 )minutes before induction and in increment doses of 0.1 mg for treatment of bradycardia. N.B. if the used anesthetic agents is cyclopropane, doses less than 0.4 mg should be used and be given slowly to avoid the possible production of ventricular arrhythmias. - For Brady arrhythmia : (0.4 -1) mg I.V. every 1 to 2 hours as needed up to 2 mg as maximum. - In cardiopulmonary resuscitation: 3 mg I.V. as a single dose to block vagal activity. - For arrhythmias after myocardial infarction: (0.3 - 1) mg I.V. if the initial dose is effective it may be repeated if necessary. - For control of muscarinic side effects of neostigmine: (0.6 - 1.2) mg I.V. - As antidote to organophosphorous insecticides: a large dose of at least (2 - 3) mg parenterally repeated until the signs of atropine intoxication appear. - As antidote to the rapid mushroom poisoning: atropine should be given in doses sufficient to control parasympathomimetic signs before coma and cardiovascular collapse supervene. Children: - For preanesthetic medication: 0.01mg in newborn infants increased to 0.06 mg in children aged 12 years to be injected S.C. 30 min. before surgery. - For bradyarrythmia: ( 0.01-0.03 )mg / kg B.W. to be injected I.V.

Adverse Reactions

The adverse effects are related to its antimuscarinic activity including:- - Transient bradycardia (followed by tachycardia, palpitations and arrhythmias). - Dilated pupils, difficulty of swallowing, thirst, hot dry skin, dizziness, restlessness, fatigue, tremors and ataxia may occur. - Constipation and difficulty in micturition may occur in elderly patients . - Hypersensitivity reactions may rarely occur such as skin rash .

Contra Indications

Atropine is contra-indicated in the following cases except in doses ordinarily for preanesthetic medication: - Angle-closure glaucoma . - In pyloric stenosis ( may be converted to complete obstruction). - In prostatic hypertrophy ( may cause urine retention). - In asthmatic patients (cause inspissations of bronchial secretions and formation of dangerous viscid plugs) . - In paralytic ileus.

Drug Interactions

- The effects of Atropine may be enhanced by concomitant use with other drugs have antimuscarinic properties as amantadine, some anti-histaminics, phenothiazine anti-psychotics , and tricyclic antidepressants . - Inhibition of drug metabolizing enzymes by MAOIs, may possible enhances the effects of antimuscarinics . - Antimuscarinics and parasympathomimetics may counteract each other effects .

Atrax 10mg | Hydroxyzine hydrochlorid

Atrax 10mg,
Each tablet contains : Hydroxyzine hydrochloride 10 mg .

Company Name
CID

Therapeutic Group
TRANQUILLIZERS

Pharmaceutical form
Tablet

Package
Box of 20 tablets

Indications
-Atarax is a drug of choice in the treatment of many dermatologic allergies specially those associated with pruritis. - Atarax is indicated for the symptomatic relief of anxiety and tension , and as an adjunct in organic disease states in which anxiety is manifested e.g. in cardiac patients to allay anxiety - Atarax is used as a sedative in : • Premedication . • Following general anesthesia. • Atarax has antiemetic effect and is used in :Post operative nausea and vomiting Motion sickness and vertigo

Warning & Precautions
- As Atarax may produce drowsiness , patients should not drive or operate machinery and should avoid alcoholic drink . - As Atarax may potentiate the effect of CNS depressant drugs, their dosage should be reduced by 50% . - The dosage should be adjusted on individual basis in preanesthetic medication and in elderly patients . - Use with caution in closed angle glaucoma , urinary retention , prostatic hypertrophy or pyloroduodenal obstruction . - In primary biliary cirrhosis adjust frequency , once daily, as elimination half-life is prolonged .

Product Type
human

Dosage
Adults - Pruritis : 25mg three or four times a day . - Anxiety : 50 to 100 mg four times a day . - Pre and post operative sedation : 50 to 100mg . Children: - Over 6 years , initial dose 10 to 25 mg daily increased if necessary to 50 to 100 mg in divided doses. - Pre and post operative sedation : 0.6 mg / kg body weight

Adverse Reactions
- Dry mouth or drowsiness may occur, it is usually mild and transitory . - With higher doses, involuntary motor activity may be seen. - Hypersensitivity reactions have occurred. - Some alterations of T-waves may occur in ECG.

Contra Indications
- Hypersensitivity to hydroxyzine. - Pregnancy specially in early months and lactation . - Patients with acute porphyria.

Drug Interactions
- Hydroxyzine may enhance the sedative effects of CNS depressants. - Hydroxyzine has an additive antimuscarinic action with other antimuscarinic drugs, such as atropine and some antidepressants.

atenolol 100 mg

Atenolol

Company Name
El Kahira

Pharmaceutical form
Tablets

Package
Boxes containing 14 tablets in one strip

Indications
Control of Hypertension: 1- Control of hypertension. 2- Management of angina pectoris. 3- Control of cardiac arrhythmias. 4- Myocardial infarction : early intervention & late intervention after myocardial infarction. 5- Used to mute the peripheral symptoms of anxiety without significantly affecting motor performance.

Warning & Precautions
Atentolol modifies tachycardia of hypoglycemia. In patients with ischemic heart disease,treatment should not be discontinued abruptly. Caution should be exercised when Atenolol is administered to nursing women,patients with poor cardiac reserve or obstructive airway disease.

Product Type
HUMAN

Dosage
100 mg once daily

Adverse Reactions
Coldness of the extremities,muscular fatigue,rarely- bradycardia and sleep disturbances.

Contra Indications
Presence of second or third heart block. Cardiogenic shock. not recommended for children.

Drug Interactions
care should be taken when using anaesthetic agents such as ether, cyclopropance and trichlorethylene.

Atenoblock | Atenoblock

Atenoblock

Each tablet contains : Atenolol 50 mg.

Company Name
CID

Pharmaceutical form
Tablet

Package
Box of 1000 tablets (100 strips of 10 tablets each ) .

Indications
• Hypertension : alone or concomitantly with other antihypertensive agents particularly with a thiazide diuretic . • Angina pectoris due to coronary atherosclerosis . • Acute myocardial infarction : to reduce cardiovascular mortality .

Warning & Precautions
- Cardiac failure : sympathetic stimulation is necessary in supporting circulatory function in congestive heart failure . - In patients with acute myocardial infarction : In cardiac failure which is not controlled by 80 mg of I.V. furosemide is contraindicated to beta – blocker treatment . - In patients with a history of cardiac failure : Depression of myocardium with beta – blocking agents may lead to cardiac failure - Concomitant use of calcium channel blockers with beta - blockers may lead to bradycardia , heart block and rise of the end of diastolic pressure of left ventricle . - Atenolol should not be used in bronchospastic disease except when bronchospastic patient does not respond to other antihypertensive. - Anesthesia and major surgery: Not advisable to withdraw beta–adrenoceptor blocking agents prior to surgery. - Diabetes and hypoglycemia : atenolol used with caution in diabetic patients if beta blocking agent is required . Use in pregnancy & lactation : • Atenolol can cause fetal harm when administered to a pregnant woman. • Caution should be exercised when atenolol is administered to a nursing women.

Product Type
human

Dosage
1 - 2 tablets according to physician instructions.

Adverse Reactions
Bradycardia , postural hypotension , heart failure , bronchospasm , peripheral vasoconstriction and gastro – intestinal upset .

Contra Indications
- Sinus bradycardia . - Heart block greater than first degree . - Cardiogenic shock . - Overt cardiac failure .

Drug Interactions
- Catecholamine – depleting drugs ( e.g. reserpine ) and also calcium channel blockers may have an additive effect when given with atenolol . - Concomitant use of prostaglandin synthase inhibiting drugs , e.g. indomethacin , may decrease the hypotensive effects of beta blockers .

Aspram 1.5 MIU | Spiramycin

Aspram 1.5 MIU

Spiramycin 1.5 M.I.U/tab.

Company Name
Alexandria

Pharmaceutical form
Tablet

Package
16 Tablets

Indications
Uses of Aspram are determined according to its anti-microbial spectrum & pharmacokinetics properties. Aspram is indicated for: Upper respiratory tract infections e.g. tonsillitis, nasopharyngitis, sinusitis and otitis. Lower respiratory tract infections e.g bronchitis and acute lung diseases. Prevention and treatment of respiratory complication of common colds and eruptive diseases. Protozoal infections e.g. toxoplasmosis.

Warning & Precautions
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Product Type
Human

Dosage
As directed by the physician or as follows: Adult dose : two tablets of 1.5 MIU twice daily . Children dose : ½ tablet of 1.5 MIU per 5 kg body weight divided in two doses.

Adverse Reactions
The most frequent side effects are gastrointestinal disturbances; skin hypersensitivity reaction have also occurred.

Contra Indications
Patients with history of hypersensitivity to spiramycin.

Drug Interactions
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Aspocid Buffer

Aspocid Buffer
Each effervescent tablet contains : Acetylsalicylic acid 325 mg .

Company Name
CID

Therapeutic Group
NON-NARCOTIC ANALGESICS

Pharmaceutical form
Eff.Tablet

Package
A carton box containing 12 effervescent tablets in Al.tubes .

Indications
- Pain . - Pyrexia ( antipyretic ) . - Rheumatic diseases . - Musculoskeletal pain . - Dysmenorrhoea . - Antiplatelet for prophylaxis of cerebrovascular diseases or myocardial infarction .

Warning & Precautions
* Acetyl salicylates should be used cautiously in the following cases: • Uncontrolled hypertension . • Elderly. • Asthmatic patients. • Renal or hepatic impairment. • Glucose-6- phosphate dehydrogenase deficiency. • Children under 12 years old. *All NSAIDs are contra-indicated in Pregnancy especially in last trimester (unlesspotential benefits overweigh risks). * It is contraindicated during lactation to avoid risk of Reye's syndrome in infants.

Product Type
human

Dosage
1-2 tablets in half a glass of water to be taken preferably after food . This dose may be repeated every ( 4 – 6 ) hours if needed , maximum 4 gm daily .

Adverse Reactions
Generally mild and infrequent including : - GIT irritation (can be reduced by taking drug after food) - Skin and bronchospastic reactions in patients who have hypersensitivity to NSAIDs. - Increased bleeding time .

Contra Indications
- Breast feeding . - Gastro–intestinal ulceration . - Hemophilia . - Gout . - History of hypersensitivity to aspirin and other NSAIDs . - Bronchial asthma .

Drug Interactions
- The risk of gastro-intestinal bleeding and ulceration associated with aspirin is increased when used with corticosteroids. - Aspirin may enhance the activity of coumarin anticoagulants, sulfonylurea hypoglycemic drugs, methotrexate, phenytoin and valproate. - Reduces the diuretic effect of spironolactone . - Reduces the excretion of acetazolamide ( increased risk of toxicity ). - Avoid concurrent administration with NSAIDs.

Aspocid 75 mg Tablets

Aspocid 75 mg Tablets
Each tablet contains : Acetylsalicylic acid 75 mg

Company Name
CID

Pharmaceutical form
Tablets

Package
A carton box containing 20 or 500 tablets in p.v.c /Al. strips each of 10 tablets .

Indications
- For adult : prophylaxis against cerebrovascular diseases or myocardial infarction. - For children : analgesic and anti-inflammatory.

Warning & Precautions
Acetyl salicylates should be used cautiously in the following cases: • Uncontrolled hypertension . • Elderly. • Asthmatic patients. • Renal or hepatic impairment. • Glucose-6- phosphate dehydrogenase deficiency. • Children under 12 years old. *All NSAIDs are contra-indicated in Pregnancy especially in last trimester (unless potential benefits overweigh risks). * It is contra-indicated during lactation to avoid risk of Reye's syndrome in infants.

Product Type
Human

Dosage
• For vascular disease: 1 tablet daily or as prescribed by the physician . • For analgesic and antipyretic effect: (2-3) tablets (4-6) times daily preferably after meals.

Adverse Reactions
- Gastro-intestinal discomfort. - Hemorrhagic disorders.

Contra Indications
• Previous or active peptic ulcer. • Hemophilia & other bleeding disorders • Bronchial asthma.

Drug Interactions
• With anticoagulants: increase risk of bleeding . • With antacids: increase aspirin excretion so decrease its effect . • With corticosteroids: increase risk of gastrointestinal bleedig. • With metoclopramide & domperidone: enhance aspirin effect .

Aspocid 300mg

Each tablet contains : Acetylsalicylic acid 300 mg .

Company Name

CID

Therapeutic Group

NON-NARCOTIC ANALGESICS

Pharmaceutical form

Tablet

Package

A carton box containing 200 tablets ( 20 strips 10 tablets of each )

Indications

- Pain . - Pyrexia (antipyretic ) . - Rheumatic diseases . - Musculoskeletal pain . - Dysmenorrhea . - Anti-platelet for initial treatment of cerebrovascular diseases or myocardial infarction

Warning & Precautions

* Acetyl salicylates should be used cautiously in the following cases: • Uncontrolled hypertension . • Elderly. • Asthmatic patients. • Renal or hepatic impairment. • Glucose-6- phosphate dehydrogenase deficiency. • Children under 12 years old. *All NSAIDs are contraindicated in Pregnancy especially in last trimester (unless potential benefits overweigh risks). * It is contraindicated during lactation to avoid risk of Reye's syndrome in infants.

Product Type

human

Dosage

Usual dose : 1 – 2 tablets to be taken preferably after food this dose may be repeated every (4-6)hours if needed , maximum 4 gm daily . *For initial treatment of cerebrovascular diseases or myocardial infarction : one tablet of Aspocid 300 to be taken once daily till reaching the desirable effect, then Aspocid 75 mg should be instituted as long term prophylaxis therapy

Adverse Reactions

Generally mild and infrequent including : - GIT irritation (can be reduced by taking drug after food) - Skin and bronchospastic reactions in patients who have hypersensitivity to NSAIDs. - Increased bleeding time .

Contra Indications

Breast-feeding . - Gastro–intestinal ulceration . - Hemophilia - Gout . - History of hypersensitivity to aspirin and other NSAIDs. - Bronchial asthma .

Drug Interactions

- The risk of gastrointestinal bleeding and ulceration associated with aspirin is increased when used with corticosteroids. - Aspirin may enhance the activity of coumarin anticoagulants, sulfonylurea hypoglycemic drugs, methotrexate, phenytoin and valproate. - Reduces the diuretic effect of spironolactone . - Reduces the excretion of acetazolamide ( increased risk of toxicity ). - Avoid concurrent administration with NSAIDs.

Aspocid – C

Each effervescent tablet contains: Acetylsalicylic acid 500 mg Ascorbic acid 250 mg

Company Name
CID

Therapeutic Group
NON-NARCOTIC ANALGESICS

Pharmaceutical form
Effervescent tablets

Package
A carton box containing 12 effervescent tablets, in aluminum tube .

Indications
Symptomatic relief of common cold and influenza .

Warning & Precautions
* Aspocid-C should be used cautiously in the following cases: • Elderly. • Asthmatic patients. • Renal or hepatic impairment. • Glucose-6- phosphate dehydrogenase deficiency. • Children under 12 years old. • Patients prone to recurrent renal calculi. * All NSAIDs are contra-indicated in Pregnancy especially in last trimester (unless potential benefits overweigh risks). * It is contra-indicated during lactation to avoid risk of Reye's syndrome in infants , maximum 4 gm daily of acetyl salicylic acid .

Product Type
human

Dosage
1-2 tablets to be taken in half a glass of water. This dose may be repeated every ( 4 - 6 ) hours if needed, maximum 4 gm daily of acetyl salicylic acid .

Adverse Reactions
Generally mild and infrequent including: • GIT irritation (can be reduced by taking drug after food ). • Skin and bronchospastic reactions in patients who have hypersensitivity toNSAIDs. • Increased bleeding time.

Contra Indications
- Breast-feeding . - Gastro–intestinal ulceration . - Hemophilia - Gout . - History of hypersensitivity to aspirin and other NSAIDs. - Bronchial asthma .

Drug Interactions
• Anticoagulants or other Antiplatelet drugs: increased risk of bleeding. • Corticosteroids: increased risk of gastrointestinal bleeding and ulceration. • Spironolactone: reduced diuretic effect. • Acetazolamide: reduced excretion of acetazolamide (increased risk of toxicity). • Acidification of urine of vitamin C may cause precipitation of urate or oxalate stones.

Aspocard 150mg

Aspocard 150mg
Each tablet contains : Acetyl salicylic acid 150 mg .

Company Name

CID

Therapeutic Group

CYCLO-OX INH PLAT AG INH

Pharmaceutical form

Chewable tablet

Package

A carton box containing 20 tablets in Al. strips ( 2 strips of 10 tablets each ) .

Indications

- For adult prophylaxis of cerebrovascular disease or myocardial infarction . - For children: as analgesic and anti-inflammatory.

Warning & Precautions

* Acetyl salicylates should be used cautiously in the following cases: • Uncontrolled hypertension . • Elderly. • Asthmatic patients. • Renal or hepatic impairment. • Glucose-6- phosphate dehydrogenase deficiency. • Children under 12 years old. *All NSAIDs are contra-indicated in Pregnancy especially in last trimester (unless potential benefits overweigh risks). * It is contra-indicated during lactation to avoid risk of Reye's syndrome in infants.

Product Type

human

Dosage

1 tablet daily or as prescribed by the physician .

Adverse Reactions

* Gastro-intestinal discomfort.

* Hemorrhagic disorders.

* Bronchospasm and skin reaction in hypersensitive patient .

Contra Indications

Children under 12 years old unless especifically indicated as in juvenile arthritis . - Previous or active peptic ulcer. - Hemophilia & other bleeding disorders - Bronchial asthma.

Drug Interactions

* Avoid concurrent administration with non-steroidal anti-inflammatory .

* Concurrent administration with anticoagulant increases the risk of bleeding

* Concurrent administration with antiepileptic enhances the effects of phenytoin and valproate .

* Corticosteroids increases the risk of gastrointestinal bleeding and ulceration .

* Cytotoxic drugs: increase the toxicity of methotrexate .

* Antagonizes diuretic effect of spirolactone and reduces the excretion of acetazolamide

Aspo Nasr 0.3 gm | Acetyl Salicylic Acid

Aspo Nasr 0.3 gm

Acetyl Salicylic Acid 300 mg

Company Name
El Nasr

Therapeutic Group
NON-NARCOTIC ANALGESICS

Pharmaceutical form
Tablet

Package
§ Box containing 30 tablets in 3 strips each enveloping 10 tablets. § Box containing 200 tablets in 20 strips each enveloping 10 tablets. § Box containing 1000 tablets in 100 strips each enveloping 10 tablets

Indications
ASPONASR Tablets indicated in patient’s headache, cold symptoms and in the long-term palliative treatment of mild to moderate pain and inflammation of arthritic and other inflammatory conditions

Warning & Precautions
General: ASPONASR Tablets Tablets should be administered with caution to patients with asthma, nasal polyps, or nasal allergies. In patients receiving large doses of aspirin and/or prolonged therapy

Product Type
Human

Dosage
Usual Adult Dosage: - One tablet ASPONASR 300 mg 3 to 4 times daily - One tablet ASPONASR 500 mg 3 to 4 times daily. . If necessary, dosage may be increased until relief is obtained,

Contra Indications
- ASPONASR Tablets Tablet should not be used in patients who have previously exhibited hypersensitivity to aspirin and/or nonsteroidal antiinflammatory agents.

Drug Interactions
Anticoagulants: See WARNINGS. Hypoglycemic Agents: See WARNINGS. Uricosuric Agents: Aspirin may decrease the effects of probenecid, sulfinpyrazone, and phenylbutazone. Spironolactone: See General PRECAUTIONS above.

Aspirin 0.5 gm | Acetyl Salicylic Acid

Aspirin 0.5 gm

Acetyl Salicylic Acid 500 mg

Company Name
El Nasr

Pharmaceutical form
Tablet

Package
Plastic bottle contains 1000 tablets. Box contains 1000 tablets each 10 Tablets packed in blister pack

Indications
ASPIRIN Tablets Tablet indicated in patient’s headache, cold symptoms and in the long-term palliative treatment of mild to moderate pain and inflammation of arthritic and other inflammatory conditions

Warning & Precautions
General: ASPIRIN Tablets Tablets should be administered with caution to patients with asthma, nasal polyps, or nasal allergies. In patients receiving large doses of aspirin and/or prolonged therapy

Product Type
Human

Dosage
Usual Adult Dosage: One tablet ASPIRIN Tablets 500 mg 3 to 4 times daily. . If necessary, dosage may be increased until relief is obtained, but dosage should be maintained slightly below that which produces tinnitus.

Contra Indications
ASPIRIN Tablets Tablet should not be used in patients who have previously exhibited hypersensitivity to aspirin and/or nonsteroidal antiinflammatory agents

Drug Interactions
Anticoagulants: See WARNINGS. Hypoglycemic Agents: See WARNINGS. Uricosuric Agents: Aspirin may decrease the effects of probenecid, sulfinpyrazone, and phenylbutazone. Spironolactone: See General PRECAUTIONS above.

Aspain | Acetylsalicylic acid

Aspain
Acetylsalicylic acid 300 mg/tab.

Company Name
Alexandria

Therapeutic Group
NON-NARCOTIC ANALGESICS

Pharmaceutical form
Tablet

Package
200 Tablets

Indications
- Headache - Muscle pain - Toothache - Menstrual pain - Pain and fever of colds - Minor pain of arthritis

Warning & Precautions
- The physician must be consulted when aspirin is used for children less than 12 years old because it may cause symptoms of Reye syndrome especially in cases of influenza and chicken box . Pregnancy: Concerning the harmful effect of acetylsalicylic acid ( Aspirin ) in the last three months of pregnancy due to the possibility of prolonging the period of pregnancy and the increased risk of antepartum and postpartum haemorrhage as well as the risk of bleeding tendency in the new born. Not to use the drug in high doses during the last three months of pregnancy. Nursing mothers : Nursing mothers should avoid using aspain because salicylate is execreted in breast milk

Product Type
Human

Dosage
As directed by the physician or as follows: Adults and children 12 years and over : 1 or 2 tablets every 4 hours, not to exceed 12 tablets in 24 hours. Children under 12 years : Consult a doctor.

Adverse Reactions
Stop use if : - Allergic reactions - Pain gets worse or lasts for more than 10 days - Fever lasts for more than 3 days - Ringing in the ears or loss of hearing occurs - Redness or swelling is present

Contra Indications
The drug is contraindicated for patients suffer from : - Allergy to aspirin or any other pain relievers / fever reducers - stomach problems ( Such as heartburn , stomach pain ) that continue or come back - Bleeding problems - ulcers - asthma Ask a doctor before use if you are taking a prescription drug for : - Anticoagulation ( blood thinning ) - Gout - Diabetes - Arthritis

Drug Interactions
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Asmacid tablets